Page 15 - Petelin, Ana. 2020. Ed. Zdravje delovno aktivne populacije / Health of the Working-Age Population. Proceedings. Koper: University of Primorska Press.
P. 15
https://doi.org/10.26493/978-961-293-015-8.13-20
Dietary polyphenols and their effect
on the gut microbiota and human health
Katja Bezek, Darja Barlič - Maganja
University of Primorska, Faculty of Health Sciences, Polje 42, 6300 Izola, Slovenia
katja.bezek@fvz.upr.si, darja.maganja@fvz.upr.si
Abstract
Problem presentation: Over the past decade the oxidative stress, caused
by reactive oxygen species (ROS) has been recognized as a key factor in
the development of various diseases e.g. diabetes, cardiovascular diseases
and neurodegenerative disorders. Antioxidant support, which can also
be provided with proper nutrition, can reduce the negative effects of
oxidative stress and have a positive effect on our health. Plant foods
are a rich source of biologically active compounds, among them many
polyphenols are very important. Due to their well-known antioxidant
properties, polyphenols are associated with a number of physiological
mechanisms that have protective effects on various organs, including
the gastrointestinal tract. Polyphenols and their metabolites help to
maintain a healthy gut primarily through microbiota modulation. They
have prebiotic-like effects, they can stimulate the growth of beneficial
and inhibit the growth of pathogenic bacteria. In addition, the gut
microbiota plays an important role in the metabolism of polyphenols,
the production of active metabolites and their bioavailability. Therefore,
the interaction between dietary polyphenols and gut microbiota can be
of significant benefit to human health. Purpose: The aim of this review
is to summarize the data on the protective role of dietary polyphenols
and their metabolites on human health in general with an emphasis on
gut microbiota modulation. Conclusions: Current research indicates
that there is a positive relationship between dietary polyphenols and the
healthy composition of the gut microbiota. Therefore, the promotion
of a diet rich in plant foods should also be considered as an important
element affecting the health of the working population.
Keywords: dietary polyphenols, gut microbiota, human health
Dietary polyphenols and their effect
on the gut microbiota and human health
Katja Bezek, Darja Barlič - Maganja
University of Primorska, Faculty of Health Sciences, Polje 42, 6300 Izola, Slovenia
katja.bezek@fvz.upr.si, darja.maganja@fvz.upr.si
Abstract
Problem presentation: Over the past decade the oxidative stress, caused
by reactive oxygen species (ROS) has been recognized as a key factor in
the development of various diseases e.g. diabetes, cardiovascular diseases
and neurodegenerative disorders. Antioxidant support, which can also
be provided with proper nutrition, can reduce the negative effects of
oxidative stress and have a positive effect on our health. Plant foods
are a rich source of biologically active compounds, among them many
polyphenols are very important. Due to their well-known antioxidant
properties, polyphenols are associated with a number of physiological
mechanisms that have protective effects on various organs, including
the gastrointestinal tract. Polyphenols and their metabolites help to
maintain a healthy gut primarily through microbiota modulation. They
have prebiotic-like effects, they can stimulate the growth of beneficial
and inhibit the growth of pathogenic bacteria. In addition, the gut
microbiota plays an important role in the metabolism of polyphenols,
the production of active metabolites and their bioavailability. Therefore,
the interaction between dietary polyphenols and gut microbiota can be
of significant benefit to human health. Purpose: The aim of this review
is to summarize the data on the protective role of dietary polyphenols
and their metabolites on human health in general with an emphasis on
gut microbiota modulation. Conclusions: Current research indicates
that there is a positive relationship between dietary polyphenols and the
healthy composition of the gut microbiota. Therefore, the promotion
of a diet rich in plant foods should also be considered as an important
element affecting the health of the working population.
Keywords: dietary polyphenols, gut microbiota, human health
