Page 65 - Petelin, Ana, Nejc Šarabon, Boštjan Žvanut, eds. 2017. Zdravje delovno aktivne populacije ▪︎ Health of the Working-Age Population. Proceedings. Koper: Založba Univerze na Primorskem/University of Primorska Press
P. 65
Ketogenic diet and its impact on mental
processes of working population
Gašper Grom
Maksimum, d. o. o., Parmova 51, 1000 Ljubljana
grom@maxximum.si
Abstract
Introduction: Ketogenic diet has been evaluated for wide variety of
conditions, although it was initially used for treatment of epilepsy. As
alternative dietary pattern it can represent means of better quality of
life, improved ability to work and can prevent against cognitive decline,
different dementias and more serious forms of neurodegenerative
diseases. Methods: This is a systematic review of available literature.
Results: As energy substrates and as signaling agents, ketones are
potentially usable in mitochondriopathies that come with aging and
neurodegenerative diseases, or are a consequence of stroke, trauma.
It has antioxidative, antiinflammatory and antiseizure properties,
improves bioenergetics of the brain, neuronal plasticity and has
epigenetic function. Discussion: Expansion of current nutritional
knowledge might be a paradigmatic shift in understanding what is
“healthy diet” in general or in terms of segments of population.
Key words: ketogenic diet, low carbohydrate, cognitive function,
neuroprotective effect
Effects of nutrition can most acutely be seen in the working population,
as it affects work efficiency and absenteeism; yet the human nutrition,
the foundation for chronic noncommunicable diseases and neurodegen-
erative diseases (ND) as well, should remain an open discussion in general.
Chronic noncommunicable diseases: cardiovascular diseases, cancer, diabetes,
musculoskeletal diseases, chronic respiratory diseases and some mental disor-
ders, are estimated to represent up to 80 % of deaths worldwide (Nacionalni in-
štitut za javno zdravje, 2017).
The public health organizations’ recommendations of the past 40 years
hardly have any positive effects. High availability of hyperpalatable food, stim-
doi: https://doi.org/10.26493/978-961-7023-32-9.63-71
processes of working population
Gašper Grom
Maksimum, d. o. o., Parmova 51, 1000 Ljubljana
grom@maxximum.si
Abstract
Introduction: Ketogenic diet has been evaluated for wide variety of
conditions, although it was initially used for treatment of epilepsy. As
alternative dietary pattern it can represent means of better quality of
life, improved ability to work and can prevent against cognitive decline,
different dementias and more serious forms of neurodegenerative
diseases. Methods: This is a systematic review of available literature.
Results: As energy substrates and as signaling agents, ketones are
potentially usable in mitochondriopathies that come with aging and
neurodegenerative diseases, or are a consequence of stroke, trauma.
It has antioxidative, antiinflammatory and antiseizure properties,
improves bioenergetics of the brain, neuronal plasticity and has
epigenetic function. Discussion: Expansion of current nutritional
knowledge might be a paradigmatic shift in understanding what is
“healthy diet” in general or in terms of segments of population.
Key words: ketogenic diet, low carbohydrate, cognitive function,
neuroprotective effect
Effects of nutrition can most acutely be seen in the working population,
as it affects work efficiency and absenteeism; yet the human nutrition,
the foundation for chronic noncommunicable diseases and neurodegen-
erative diseases (ND) as well, should remain an open discussion in general.
Chronic noncommunicable diseases: cardiovascular diseases, cancer, diabetes,
musculoskeletal diseases, chronic respiratory diseases and some mental disor-
ders, are estimated to represent up to 80 % of deaths worldwide (Nacionalni in-
štitut za javno zdravje, 2017).
The public health organizations’ recommendations of the past 40 years
hardly have any positive effects. High availability of hyperpalatable food, stim-
doi: https://doi.org/10.26493/978-961-7023-32-9.63-71
