Page 137 - Petelin, Ana. 2020. Zdravje delovno aktivne populacije / Health of the Working-Age Population. Zbornik povzetkov z recenzijo ▪︎ Book of Abstracts. Koper: Založba Univerze na Primorskem/University of Primorska Press
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role of prebiotics and probiotics after gastrointestinal surgery prehrana in hidracija | nutrition and hydration
Zdravko Štor
University Medical Centre Ljubljana, Zaloška cesta 7, 1000 Ljubljana, Slovenia
Starting and purpose: The intestinal microflora, as an important part of the in-
testinal immune and non-immune defenses, is the basis of the concept of pro-
biotics. These are living microorganisms added to food in sufficient quantities,
which affect the improvement of the intestinal flora and affect health.
Presentation: The most important mechanisms of action of prebiotics and pro-
biotics are the synthesis of antimicrobial substances, consumption of nutrients
necessary for the growth of pathogenic flora, inhibition of adhesion of patho-
genic bacteria, modification of toxins and toxin receptors, activation of the im-
mune system by increasing the production of secretory immunoglobulins.
Intestinal microflora can be the source of many complications after surgery,
due to a dysfunctional intestinal barrier and bacterial translocation. Probiotics
can have a beneficial effect on the intestinal barrier and reduce the incidence of
infections in this group of patients.
Conclusion: Probiotics are also increasingly used in hospitals to prevent no-
socomial infections. An example of such use is the prevention of infections
after gastrointestinal surgery by adding probiotics or synbiotics (mixtures of
probiotics and prebiotics). Studies have shown a reduced incidence of surgical
wound infection using probiotics or synbiotics. They also found a reduced in-
cidence of diarrhoea, a reduced incidence of intestinal obstruction, a reduced
number of common infections and a reduced number of pneumonias.
Key words: prebiotics, probiotics, gastrointestinal surgery
135
Zdravko Štor
University Medical Centre Ljubljana, Zaloška cesta 7, 1000 Ljubljana, Slovenia
Starting and purpose: The intestinal microflora, as an important part of the in-
testinal immune and non-immune defenses, is the basis of the concept of pro-
biotics. These are living microorganisms added to food in sufficient quantities,
which affect the improvement of the intestinal flora and affect health.
Presentation: The most important mechanisms of action of prebiotics and pro-
biotics are the synthesis of antimicrobial substances, consumption of nutrients
necessary for the growth of pathogenic flora, inhibition of adhesion of patho-
genic bacteria, modification of toxins and toxin receptors, activation of the im-
mune system by increasing the production of secretory immunoglobulins.
Intestinal microflora can be the source of many complications after surgery,
due to a dysfunctional intestinal barrier and bacterial translocation. Probiotics
can have a beneficial effect on the intestinal barrier and reduce the incidence of
infections in this group of patients.
Conclusion: Probiotics are also increasingly used in hospitals to prevent no-
socomial infections. An example of such use is the prevention of infections
after gastrointestinal surgery by adding probiotics or synbiotics (mixtures of
probiotics and prebiotics). Studies have shown a reduced incidence of surgical
wound infection using probiotics or synbiotics. They also found a reduced in-
cidence of diarrhoea, a reduced incidence of intestinal obstruction, a reduced
number of common infections and a reduced number of pneumonias.
Key words: prebiotics, probiotics, gastrointestinal surgery
135
