Page 139 - Petelin, Ana. 2020. Zdravje delovno aktivne populacije / Health of the Working-Age Population. Zbornik povzetkov z recenzijo ▪︎ Book of Abstracts. Koper: Založba Univerze na Primorskem/University of Primorska Press
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tary polyphenols and their effect on the gut microbiota prehrana in hidracija | nutrition and hydration
and human health
Katja Bezek, Darja Barlič – Maganja
University of Primorska, Faculty of Health Sciences, Polje 42, 6310 Izola, Slovenia
Purpose: The aim of this review was to summarize the data on the protective
role of dietary polyphenols and their metabolites on human health in general
with an emphasis on gut microbiota modulation.
Content presentation: Over the past decade the oxidative stress, caused by
reactive oxygen species (ROS) has been recognized as a key factor in the de-
velopment of various diseases e.g. diabetes, cardiovascular diseases and neu-
rodegenerative disorders. Antioxidant support, which can also be provided
with proper nutrition, can reduce the negative effects of oxidative stress and
have a positive effect on our health. Plant foods are a rich source of biological-
ly active compounds, among them many polyphenols are very important. Due
to their well-known antioxidant properties, polyphenols are associated with
a number of physiological mechanisms that have protective effects on various
organs, including the gastrointestinal tract. Polyphenols and their metabolites
help healthy gut maintenance primarily through microbiota modulation. They
have prebiotic-like effects, they can stimulate the growth of beneficial and in-
hibit the growth of pathogenic bacteria. In addition, the gut microbiota plays an
important role in the metabolism of polyphenols, the production of active me-
tabolites and their bioavailability. Therefore, the interaction between dietary
polyphenols and gut microbiota can be of significant benefit to human health.
Conclusions: Current research indicates that there is a positive relationship be-
tween dietary polyphenols and the healthy composition of the gut microbiota.
Therefore, the promotion of a diet rich in plant foods should also be consid-
ered as an important element affecting the health of the working population.
Key words: dietary polyphenols, gut microbiota, human health
137
and human health
Katja Bezek, Darja Barlič – Maganja
University of Primorska, Faculty of Health Sciences, Polje 42, 6310 Izola, Slovenia
Purpose: The aim of this review was to summarize the data on the protective
role of dietary polyphenols and their metabolites on human health in general
with an emphasis on gut microbiota modulation.
Content presentation: Over the past decade the oxidative stress, caused by
reactive oxygen species (ROS) has been recognized as a key factor in the de-
velopment of various diseases e.g. diabetes, cardiovascular diseases and neu-
rodegenerative disorders. Antioxidant support, which can also be provided
with proper nutrition, can reduce the negative effects of oxidative stress and
have a positive effect on our health. Plant foods are a rich source of biological-
ly active compounds, among them many polyphenols are very important. Due
to their well-known antioxidant properties, polyphenols are associated with
a number of physiological mechanisms that have protective effects on various
organs, including the gastrointestinal tract. Polyphenols and their metabolites
help healthy gut maintenance primarily through microbiota modulation. They
have prebiotic-like effects, they can stimulate the growth of beneficial and in-
hibit the growth of pathogenic bacteria. In addition, the gut microbiota plays an
important role in the metabolism of polyphenols, the production of active me-
tabolites and their bioavailability. Therefore, the interaction between dietary
polyphenols and gut microbiota can be of significant benefit to human health.
Conclusions: Current research indicates that there is a positive relationship be-
tween dietary polyphenols and the healthy composition of the gut microbiota.
Therefore, the promotion of a diet rich in plant foods should also be consid-
ered as an important element affecting the health of the working population.
Key words: dietary polyphenols, gut microbiota, human health
137
